ANTIDIABETIC ACTIVITY OF GLADIOLUS PSITTASCINUS IN ALLOXAN INDU-CED DIABETIC RATS.

Authors

  • Adediwura Fred-Jaiyesimi
  • Kio Abo

Keywords:

Gladiolus psittascinus, hypoglycaemic activity, diabetes mellitus.

Abstract

The methanol extract of Gladiolus psittascinus bulb was evaluated for its antidiabetic activities in alloxan-induced diabetic rats. Blood glucose levels of the glucose loaded and alloxan-induced diabetic rats were estimated over 180 minutes using the O-toluidine and glucose-oxidase methods. The methanol extract at 1g/kg dose exhibited 16.2% decrease in blood glucose level in the glucose loaded rats and a peak effect of 78.9% in the alloxan-induced diabetic rats. The extract exhibited significant blood glucose lowering effects in the oral glucose tolerance test and type 2 diabetic rats. This study shows a possible beneficial effect of Gladiolus psittascinus in the management of non-insulin dependent diabetes (NIDDM).

Author Biography

Adediwura Fred-Jaiyesimi

Department of Pharmacognosy, Faculty of Pharmacy, Olabisi Onabanjo University. Sagamu. Ogun State. Nigeria,

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Published

2007-09-26

How to Cite

Fred-Jaiyesimi, A., & Abo, K. (2007). ANTIDIABETIC ACTIVITY OF GLADIOLUS PSITTASCINUS IN ALLOXAN INDU-CED DIABETIC RATS. African Journal of Traditional, Complementary and Alternative Medicines, 5(2), 154–157. Retrieved from https://journals.athmsi.org/index.php/ajtcam/article/view/283

Issue

Vol. 5 No. 2 (2008)

Section

Research Papers

License

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