ANTIMICROBIAL EFFECTS OF THE STEM BARK EXTRACTS OF PARKIA BIGLOBOSA (JACQ.)BENTH. ON SHIGELLAE

Authors

  • H. Millogo-Kone
  • I. P. Guissou
  • O. Nacoulma
  • A. S. Traore

Keywords:

Shigellae – Hydroalcoholic extract – bark – Parkia biglobosa

Abstract

Total and hydroalcoholic extracts of the stem barks of Parkia biglobosa (Jacq) Benth. (Mimosaceae) were tested on strains belonging to three species of Shigellae: S. dysenteriae, S. flexneri and S. boydii collected from hospitals in Ouagadougou, Burkina Faso. The results showed that both extracts were active against Shigellae. The hydroalcoholic extract was more active than the decoction (aqueous one) prescribed by the traditional healer. Both extracts were particularly effective against S. dysenteriae, the most virulent of the three pathogenic species. The effects of the extracts have been compared to that of gentamicin. The phytochemical screening on the extracts revealed the presence of sterols, triterpenes, polyphenolic compounds including tanins, flavonoids, coumarins, anthocyanidins. Other components are saponosides and reducing sugars.

Author Biographies

H. Millogo-Kone

Centre National de la Recherche Scientifique et Technologique(CNRST)– Institut de Recherche en Sciences de la Santé (IRSS) – Département Médecine et Pharmacopée Traditionnelles – Pharmacie (MEPHATRA/PH) - 03 B.P. 7192 – Ouagadougou 03 - Burkina Faso

I. P. Guissou

Centre National de la Recherche Scientifique et Technologique(CNRST)– Institut de Recherche en Sciences de la Santé (IRSS) – Département Médecine et Pharmacopée Traditionnelles – Pharmacie (MEPHATRA/PH) - 03 B.P. 7192 – Ouagadougou 03 - Burkina Faso

O. Nacoulma

Université de Ouagadougou – 03 B.P. 7021 Ouagadougou, 03 – Burkina Faso – UFR/SDS et UFR/SVT

A. S. Traore

Université de Ouagadougou – 03 B.P. 7021 Ouagadougou, 03 – Burkina Faso – UFR/SDS et UFR/SVT

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Published

2007-06-10

How to Cite

Millogo-Kone, H., Guissou, I. P., Nacoulma, O., & Traore, A. S. (2007). ANTIMICROBIAL EFFECTS OF THE STEM BARK EXTRACTS OF PARKIA BIGLOBOSA (JACQ.)BENTH. ON SHIGELLAE. African Journal of Traditional, Complementary and Alternative Medicines, 4(4), 392 –. Retrieved from https://journals.athmsi.org/index.php/ajtcam/article/view/266

Issue

Vol. 4 No. 4 (2007)

Section

Research Papers

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