TY - JOUR AU - Zheng, Yu AU - Wang, Yuying AU - Lan, Yujun AU - Qu, Xiaodong AU - Lin, Kelin AU - Zhang, Jiping AU - Qu, Shanshan AU - Wang, Yanjie AU - Tang, Chunzhi AU - Huang, Yong PY - 2016/09/29 Y2 - 2024/03/29 TI - IMAGING OF BRAIN FUNCTION BASED ON THE ANALYSIS OF FUNCTIONAL CONNECTIVITY - IMAGING ANALYSIS OF BRAIN FUNCTION BY FMRI AFTER ACUPUNCTURE JF - African Journal of Traditional, Complementary and Alternative Medicines JA - Afr J Tradit Complement Altern Med VL - 13 IS - 6 SE - Research Papers DO - 10.21010/ajtcam.v13i6.14 UR - https://journals.athmsi.org/index.php/ajtcam/article/view/4262 SP - 90-100 AB - Objective: This Study observed the relevant brain areas activated by acupuncture at the Taichong acupoint (LR3) and analyzed thefunctional connectivity among brain areas using resting state functional magnetic resonance imaging (fMRI) to explore the acupointspecificity of the Taichong acupoint.Methods: A total of 45 healthy subjects were randomly divided into the Taichong (LR3) group, sham acupuncture group and shamacupoint group. Subjects received resting state fMRI before acupuncture, after true (sham) acupuncture in each group. Analysis ofchanges in connectivity among the brain areas was performed using the brain functional connectivity method.Results: The right cerebrum temporal lobe was selected as the seed point to analyze the functional connectivity. It had a functionalconnectivity with right cerebrum superior frontal gyrus, limbic lobe cingulate gyrus and left cerebrum inferior temporal gyrus (BA37), inferior parietal lobule compared by before vs. after acupuncture at LR3, and right cerebrum sub-lobar insula and left cerebrummiddle frontal gyrus, medial frontal gyrus compared by true vs. sham acupuncture at LR3, and right cerebrum occipital lobe cuneus,occipital lobe sub-gyral, parietal lobe precuneus and left cerebellum anterior lobe culmen by acupuncture at LR3 vs. sham acupoint.Conclusion: Acupuncture at LR3 mainly specifically activated the brain functional network that participates in visual function,associative function, and emotion cognition, which are similar to the features on LR3 in tradition Chinese medicine. These brainareas constituted a neural network structure with specific functions that had specific reference values for the interpretation of theacupoint specificity of the Taichong acupoint. ER -