ANTI-ALLERGIC, ANTI-PRURITIC, AND ANTI-INFLAMMATORY ACTIVITIES OF CENTELLA ASIATICA EXTRACTS

Authors

  • M. George
  • L. Joseph
  • - Ramaswamy

Keywords:

Anti-pruritic, Anti-allergic, Anti-inflammatory, Centella asiatica extract .

Abstract

This study investigated antipruritic and anti-inflammatory effect of Centella asiatica extract in rats and anti-allergic in vitro using sheep (Capra hircus ) serum method and compound 48/80 induced mast cell degranulation method, compared with standard drug ketotifen fumarate. In rats, extract of Centella asiatica administered orally was examined for anti-pruritic study and chlorpheniramine maleate was used as standard drug while carageenan paw induced inflammatory method was used for the antiinfammatory study. The results show that the extracts of Centella asiatica exhibited antiallergic, anti-pruritic and anti-inflammatory activities.

Author Biography

M. George

Mekelle University, Mekelle,Ethiopia

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Published

2009-06-08

How to Cite

George, M., Joseph, L., & Ramaswamy, .-. (2009). ANTI-ALLERGIC, ANTI-PRURITIC, AND ANTI-INFLAMMATORY ACTIVITIES OF CENTELLA ASIATICA EXTRACTS. African Journal of Traditional, Complementary and Alternative Medicines, 6(4), 554–559. Retrieved from https://journals.athmsi.org/index.php/ajtcam/article/view/968

Issue

Section

Research Papers