ANTIMICROBIAL ACTIVITY OF TRADITIONALLY USED INDIGENOUS MEDICINAL PLANT FROM LIMPOPO PROVINCE

Authors

  • M. Mokgotho
  • P. Masoko
  • V. Mbazima
  • J. N. Eloff
  • R. Howard
  • L. Mampuru

Abstract

Plant extracts have been known since antiquity to possess notable biological activity including antioxidant, antibacterial and antifungal properties. Commelina benghalesis L has been used traditionally to alleviate diseases and aliments of skin. The antioxidant and antibacterial activities of the plant extracts were evaluated. Four solvents (hexane, DCM, acetone and methanol) were used for preparation of extracts. TLC profiles for all the extracts did not show any compound having antioxidant activity against DPPH radical molecule. Bioautography revealed several compounds having antibacterial activity. The hexane extract had a relatively higher activity compared to other extracts. However, when quantifying the activity, DCM extract showed a better MIC values compared to other extracts.

Author Biography

M. Mokgotho

Biochemistry, Microbiology and Biotechnology Department, University of Limpopo, Sovenga, South Africa, Limpopo Province, 0727

Published

2009-05-04

How to Cite

Mokgotho, M., Masoko, P., Mbazima, V., Eloff, J. N., Howard, R., & Mampuru, L. (2009). ANTIMICROBIAL ACTIVITY OF TRADITIONALLY USED INDIGENOUS MEDICINAL PLANT FROM LIMPOPO PROVINCE. African Journal of Traditional, Complementary and Alternative Medicines, 6, 450. Retrieved from https://journals.athmsi.org/index.php/ajtcam/article/view/883

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