GENETIC AND PHYTOCHEMICAL VARIATION IN PLANTAGO MAJOR
Abstract
Leaves of the common weed Plantago major (common plantain) have been used as a wound healing remedy in almost all parts of the world, and in the treatment of a number of other diseases in folk medicine. The biological activities of P. major leaves are wound healing, anti-inflammatory, analgesic, antioxidant, weakly antibiotic, immuno-modulating and anti-ulcerogenic. The aim of study is to develop: 1. Plantago major, well-known from folk medicine, into a modern medicinal herb, 2. Optimize organic cultivation procedures to produce leaf extracts for use in a superior, biologically active wound dressing. DNA analyses (RAPD) will be conducted for determining genetic variation among populations and for checking homogeneity in offspring from selected mother plants. Chemical analyses (HPLC and mass chromatography) will be performed in order to study different polyphenolic compounds (flavonoids, phenylpropanoid glycosides and iridoids) that are likely to be involvd in the wound-healing ability of P. major. Greenhouse cultvation experiments will be undertaken to check the effects of different levels of light supplementation, heating and fertilization.Published
How to Cite
Issue
Section
License
Copyright: Creative Commons Attribution CC.
This license lets others distribute, remix, tweak, and build upon your work, even commercially, as long as they credit you for the original creation. This is the most accommodating of licenses offered. Recommended for maximum dissemination and use of licensed materials. View License Deed | View Legal Code Authors can also self-archive their manuscripts immediately and enable public access from their institution's repository. This is the version that has been accepted for publication and which typically includes author-incorporated changes suggested during submission, peer review and in editor-author communications.