CARDIOVASCULAR EFFECTS OF HARPAGOPHYTUM PROCUMBENS DC

Authors

  • Ismail M. Mahomed
  • John Akanni O. Ojewole

Keywords:

Harpagophytum procumbens, cardiovascular effects.

Abstract

In an attempt to scientifically appraise the ‘healing powers’ and medicinal value of Harpagophytum procumbens DC root aqueous extract (HPE), and throw some light on the efficacy and safety of the medicinal plant product, the cardiovascular effects of the herb’s root aqueous extract (HPE) have been investigated in some mammalian experimental animal models. The results of this laboratory animal study indicate that relatively low to moderate doses of H. procumbens root aqueous extract (HPE, 10–400 mg/kg i. v.) produced dose-dependent hypotensive and cardio-depressant effects on systemic arterial blood pressures and heart rates of pentobarbitone-anaesthetized rats. Relatively low to high concentrations of the plant’s extract (HPE, 10–1000

Author Biographies

Ismail M. Mahomed

Department of Pharmacology, Faculty of Health Sciences, University of KwaZulu-Natal, Private Bag X54001, Durban 4000, South Africa

John Akanni O. Ojewole

Department of Pharmacology, Faculty of Health Sciences, University of KwaZulu-Natal, Private Bag X54001, Durban 4000, South Africa

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Published

2006-01-07

How to Cite

Mahomed, I. M., & Ojewole, J. A. O. (2006). CARDIOVASCULAR EFFECTS OF HARPAGOPHYTUM PROCUMBENS DC. African Journal of Traditional, Complementary and Alternative Medicines, 1(1), 30–44. Retrieved from https://journals.athmsi.org/index.php/ajtcam/article/view/63

Issue

Vol. 1 No. 1 (2004)

Section

Research Papers

License

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