Vol 17 No 2 (2020)
Review

STRYCHNOS SPINOSA LAM: COMPREHENSIVE REVIEW ON ITS MEDICINAL AND NUTRITIONAL USES.

Nassifatou Koko Tittikpina
Universite de Lome (University of Lome)
Wouyo Atakpama
Laboratoire de Botanique et Ecologie Végétale, Université de Lomé (University of Lomé), 01 BP 1515, Lomé 01, Togo.
Yao Hoekou
Laboratoire des Sciences Biomédicales, Alimentaires et de Santé Environnementale (LaSBASE), Ecole Supérieure des Techniques Biologiques et Alimentaires, Université de Lomé, 01 BP 1515, Lomé 01, Togo.
Yerim Mbagnick Diop
Laboratoire de Chimie Analytique et Bromatologie (LCAB), Faculté de Médecine, de Pharmacie et d'Odontologie, UCAD, BP 5005, Dakar, Sénégal.
Komlan Batawila
Laboratoire de Botanique et Ecologie Végétale, Université de Lomé (University of Lomé), 01 BP 1515, Lomé 01, Togo.
Komlan Akpagana
Laboratoire de Botanique et Ecologie Végétale, Université de Lomé (University of Lomé), 01 BP 1515, Lomé 01, Togo.
Published November 18, 2020
Keywords
  • Strychnos spinosa, ethnobotany, pharmacological activities, biological activities, nutrition, phytochemistry.
How to Cite
Tittikpina, N., Atakpama, W., Hoekou, Y., Diop, Y., Batawila, K., & Akpagana, K. (2020). STRYCHNOS SPINOSA LAM: COMPREHENSIVE REVIEW ON ITS MEDICINAL AND NUTRITIONAL USES. African Journal of Traditional, Complementary and Alternative Medicines, 17(2), 8-28. Retrieved from https://journals.athmsi.org/index.php/ajtcam/article/view/5757

Abstract

Background: Most of the people living in developing countries rely on local remedies from traditional medicines to take care of their healthcare needs. In recent years, the use of medicinal plants increased considerably. Consequently, studies on medicinal plants are necessary to produce more effective drugs with fewer side-effects. This work aims to compile the dispersal data on Strychnos spinosa Lam., a medicinal plant with great therapeutic potential in traditional medicine, on its ethnobotanical uses, chemical compounds, as well as its pharmacological and nutritional effects.

Material and Methods: To achieve the aforementioned aim, electronic databases such as Pubmed, Science Direct, Google scholar, Scopus and SciFinder were scanned.

Results:  Literature survey revealed that S. spinosa is used in the treatment of microbial infections, malaria, trypanosomiasis, intestinal worms, tuberculosis, infertility, gastrointestinal disorders, snake bite, hypertension, and diabetes mellitus among other ailments. The plant is also used as food material. S. spinosa contains many chemical compounds, such as alkaloids, terpenes, sterols, fatty acids, flavonoids, saponin, and others. The fruits are a source of important nutrients such as carbohydrates, sugars, proteins, vitamins and fibres. Experimental studies have shown numerous pharmacological properties, including antimicrobial, antiplasmodial, anti-trypanosomal, anti-leishmanial, anti-nematicidal, anti-inflammatory, anti-oxidant, antidiabetic and other activities.

Conclusion: This review article provides comprehensive information on S. spinosa and its various extracts. Due to the promising effects of the plant extracts on various diseases and its nutritional values, there is a need for toxicity studies and clinical trials to assess the effects of its identified bioactive compounds.