MORINGA OLEIFERA LEAF POWDER FOR TYPE 2 DIABETES: A PILOT CLINICAL TRIAL

Authors

  • Lassana Sissoko 1. Département de Médecine Traditionnelle, Institut National de Recherche en Santé Publique, BP 1746, Bamako, Mali
  • Nouhoum Diarra 2. l’Université des Sciences, des Techniques et des Technologies de Bamako, Bamako, Mali
  • Ibrahim Nientao ONG Santé Diabète Mali, Bamako, Mali
  • Beth Stuart 4. School of Primary Care, Population Sciences, and Medical Education, University of Southampton, Aldermoor Health Centre, Aldermoor Close, Southampton SO16 5ST, UK
  • Adiaratou Togola Département de Médecine Traditionnelle, Institut National de Recherche en Santé Publique, BP 1746, Bamako, Mali
  • Drissa Diallo Département de Médecine Traditionnelle, Institut National de Recherche en Santé Publique, BP 1746, Bamako, Mali
  • Merlin Luke Willcox RITAM

DOI:

https://doi.org/10.21010/Ajtcamv17i2.3

Keywords:

Moringa oleifera, clinical trial, Type 2 diabetes

Abstract

Background: Moringa oleifera Lam. (Moringaceae) leaves are commonly used for diabetes in Mali. This pilot clinical study aimed to evaluate its effect on post-prandial blood glucose in preparation for a larger trial.

Methods: Diabetic patients and non-diabetic healthy volunteers (35 each) were asked to fast for 13 hours on three occasions. Blood glucose was measured before and after eating 100g of white bread (at 30, 60, 90, 120, 150 and 180 minutes). On their second and third study visits, they were given 1g and 2g respectively, of M. oleifera leaf powder, 30 minutes after eating the bread.  The mean paired reduction in blood glucose at each time interval and the incremental area under the curve were calculated.

Results: Ingestion of Moringa powder had no effect on blood glucose in non-diabetic participants, but in diabetic patients, it lowered blood glucose at 90 minutes. There was a trend towards lower incremental area under the curve when diabetic patients took 2g of Moringa. No side-effects were reported by any participant.

Conclusions: Moringa oleifera leaf powder reduced post-prandial glycaemia in diabetic patients. A larger study is needed to define the optimal dose and to assess whether this translates into longer-term benefits.

Author Biography

Merlin Luke Willcox, RITAM

Honorary Secretary, Research Initiative for Traditional Antimalarial Methods

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Published

2023-02-17

How to Cite

Sissoko, L., Diarra, N., Nientao, I., Stuart, B., Togola, A., Diallo, D., & Willcox, M. L. (2023). MORINGA OLEIFERA LEAF POWDER FOR TYPE 2 DIABETES: A PILOT CLINICAL TRIAL. African Journal of Traditional, Complementary and Alternative Medicines, 17(2), 29–36. https://doi.org/10.21010/Ajtcamv17i2.3

Issue

Vol. 17 No. 2 (2020)

Section

Research Papers

License

Copyright (c) 2023 Lassana Sissoko, Nouhoum Diarra, Ibrahim Nientao, Beth Stuart, Adiaratou Togola, Drissa Diallo, Merlin Luke Willcox

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