Vol 17 No 2 (2020)
Research Papers

MORINGA OLEIFERA LEAF POWDER FOR TYPE 2 DIABETES: A PILOT CLINICAL TRIAL

Lassana Sissoko
1. Département de Médecine Traditionnelle, Institut National de Recherche en Santé Publique, BP 1746, Bamako, Mali
Nouhoum Diarra
2. l’Université des Sciences, des Techniques et des Technologies de Bamako, Bamako, Mali
Ibrahim Nientao
ONG Santé Diabète Mali, Bamako, Mali
Beth Stuart
4. School of Primary Care, Population Sciences, and Medical Education, University of Southampton, Aldermoor Health Centre, Aldermoor Close, Southampton SO16 5ST, UK
Adiaratou Togola
Département de Médecine Traditionnelle, Institut National de Recherche en Santé Publique, BP 1746, Bamako, Mali
Drissa Diallo
Département de Médecine Traditionnelle, Institut National de Recherche en Santé Publique, BP 1746, Bamako, Mali
Merlin Luke Willcox
RITAM
Bio
Published November 18, 2020
Keywords
  • Moringa oleifera,
  • clinical trial,
  • Type 2 diabetes
How to Cite
Sissoko, L., Diarra, N., Nientao, I., Stuart, B., Togola, A., Diallo, D., & Willcox, M. (2020). MORINGA OLEIFERA LEAF POWDER FOR TYPE 2 DIABETES: A PILOT CLINICAL TRIAL. African Journal of Traditional, Complementary and Alternative Medicines, 17(2), 29-36. Retrieved from https://journals.athmsi.org/index.php/ajtcam/article/view/5693

Abstract

Background

Moringa oleifera Lam. (Moringaceae) leaves are commonly used for diabetes in Mali. This pilot clinical study aimed to evaluate its effect on post-prandial blood glucose in preparation for a larger trial.

Methods

Diabetic patients and non-diabetic healthy volunteers (35 each) were asked to fast for 13 hours on three occasions. Blood glucose was measured before and after eating 100g of white bread (at 30, 60, 90, 120, 150 and 180 minutes). On their second and third study visits, they were given 1g and 2g respectively of M. oleifera leaf powder, 30 minutes after eating the bread. We calculated the mean paired reduction in blood glucose at each time interval and the incremental area under the curve.

Results

Ingestion of Moringa powder had no effect on blood glucose in non-diabetic participants, but in diabetic patients, it lowered blood glucose at 90 minutes. There was a trend towards lower incremental area under the curve when diabetic patients took 2g of Moringa. No side-effects were reported by any participants.

Conclusions

Moringa oleifera leaf powder reduced post-prandial glycaemia in diabetic patients. A larger study is needed to define the optimal dose and to assess whether this translates into longer-term benefits.