Vol 14 No 3 (2017)
Short communications

ANTI-VIRAL EFFECT OF HERBAL MEDICINE KOREAN TRADITIONAL CYNANCHUM PANICULATUM (BGE.) KITAG EXTRACTS

Published March 1, 2017
Keywords
  • Antiviral,
  • Bovine viral diarrhoea(BVD) virus,
  • Cynanchum paniculatum (Bge.) Kitag.Ethly acetate extract.
How to Cite
Kim, W., Oh, T.-S., & Park, Y.-J. (2017). ANTI-VIRAL EFFECT OF HERBAL MEDICINE KOREAN TRADITIONAL CYNANCHUM PANICULATUM (BGE.) KITAG EXTRACTS. African Journal of Traditional, Complementary and Alternative Medicines, 14(3), 194-198. https://doi.org/10.21010/ajtcam.v14i3.21

Abstract

Background: Pestiviruses in general, and Bovine Viral Diarrhea (BVD) in particular, present several potential targets for directed antiviral therapy. Material and Methods: The antiviral effect of Cynanchum paniculatum (Bge.) Kitag (Dog strangling vine: DS) extract on the bovine viral diarrhea (BVD) virus was tested. First, a cytotoxicity test in MDBK (Madin-Darby bovine kidney) cells was done with all organic extract concentrations. Results: The cytotoxic concentration CC50 for the ethyl acetate (EA) extracts was 18.2 ug/ml. In the tissue culture, infectious dose (TCID50) assay, the BVD virus decreased when treated with 18.2 ug/ml of the ethyl acetate extracts. Conclusion: Ethyl acetate extracts and fractions of the DS extract could be used as a potential antiviral for BVD.