ANTIULCEROGENIC ACTIVITY OF ETHANOLIC LEAF EXTRACT OF LASIANTHERA AFRICANA

Authors

  • Jude E. Okokon DEPT.OF PHARMACOLOGY AND TOXICOLOGY,FACULTY OF PHARMACY,UNIVERSITY OF UYO,UYO,NIGERIA
  • Bassey S. Antia 2. Dept. of Chemistry,University of Uyo, Uyo, Nigeria
  • Emem E. Umoh 3.DEPT.OF PHARMACOLOGY AND TOXICOLOGY,FACULTY OF PHARMACY,UNIVERSITY OF UYO,UYO,NIGERIA

Keywords:

Lasianthera africana, antiulcer, vegetable

Abstract

The effect of ethanolic leaf extract of Lasianthera africana on experimentally induced ulcer was studied in rats. The extract (1000 – 3000mg/kg) inhibited ethanol-induced, indomethacin – induced and reserpine –induced ulcer models in a dose dependent fashion. The various degrees of inhibitions were statistically significant (p<0.01). The effect of the extract was comparable to that of the standard drugs used. Thus, Lasianthera africana extract demonstrated a good antiulcer activity which supports the antiulcer effect of this plant in traditional medicine.

Author Biographies

Jude E. Okokon, DEPT.OF PHARMACOLOGY AND TOXICOLOGY,FACULTY OF PHARMACY,UNIVERSITY OF UYO,UYO,NIGERIA

DEPT OF PHARMACOLOGY AND TOXICOLOGY,LECTURER 1

Bassey S. Antia, 2. Dept. of Chemistry,University of Uyo, Uyo, Nigeria

2. Dept. of Chemistry,University of Uyo, Uyo, Nigeria,seniorlecturer

Emem E. Umoh, 3.DEPT.OF PHARMACOLOGY AND TOXICOLOGY,FACULTY OF PHARMACY,UNIVERSITY OF UYO,UYO,NIGERIA

3. DEPT OF PHARMACOLOGY AND TOXICOLOGY,LECTURER 1

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Published

2009-03-07

How to Cite

Okokon, J. E., Antia, B. S., & Umoh, E. E. (2009). ANTIULCEROGENIC ACTIVITY OF ETHANOLIC LEAF EXTRACT OF LASIANTHERA AFRICANA. African Journal of Traditional, Complementary and Alternative Medicines, 6(2), 150–154. Retrieved from https://journals.athmsi.org/index.php/ajtcam/article/view/463

Issue

Vol. 6 No. 2 (2009)

Section

Research Papers

License

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