IN VITRO AMOEBICIDAL ACTIVITY OF SOME MEDICINAL PLANTS OF THE BAMUN REGION (CAMEROON)

Authors

  • Paul F. Moundipa
  • Kamini G. Melanie Flore
  • Charles F. Bilong
  • Iris Bruchhaus

Keywords:

Medicinal plants, Codiaeum variegatum, In vitro, amoebicidal, Bamun, Cameroon.

Abstract

Fifty two medicinal plants belonging to different families selected on the basis of their traditional use against jaundice and various liver disorders were tested for their amoebicidal activities. They were extracted and tested for their antiamoebic activity in vitro using polyxenic culture of Entamoebic histolytica. As the result, 14 exhibited an antiamoebic activity at a dose of 100µg/ml from the second to the fourth day of incubation. The 14 selected extracts were additionaly tested for 6 days at 10, 100 and 500g/ml of concentration, and only the leaves extract of Codiaeum variegatum exhibited a clear antiamoebic activity (EC50=10,74 the second day), and had a more pronounced activity than metronidazole the reference product.

Author Biographies

Paul F. Moundipa

Laboratory of Biochemical Toxicology and Nutrition Department of Biochemistry, University of Yaounde I

Kamini G. Melanie Flore

Laboratory of Biochemical Toxicology and Nutrition Department of Biochemistry, University of Yaounde I

Charles F. Bilong

Laboratory of General Biology, University of Yaounde I,

Iris Bruchhaus

Bernhard Nocht Institute for Tropical Medicine, University of Hamburg, Germany.

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Published

2006-01-07

How to Cite

Moundipa, P. F., Melanie Flore, K. G., Bilong, C. F., & Bruchhaus, I. (2006). IN VITRO AMOEBICIDAL ACTIVITY OF SOME MEDICINAL PLANTS OF THE BAMUN REGION (CAMEROON). African Journal of Traditional, Complementary and Alternative Medicines, 2(2), 113 –. Retrieved from https://journals.athmsi.org/index.php/ajtcam/article/view/44

Issue

Vol. 2 No. 2 (2005)

Section

Research Papers

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