RENAL ISCHEMIA REPERFUSION CAUSES BRAIN HIPPOCAMPUS OXIDATIVE DAMAGE AND INHIBITION EFFECT

Authors

  • Fang Yu
  • Haidong Liang
  • Shimeng Xin

DOI:

https://doi.org/10.21010/ajtcam.v13i5.9

Keywords:

Kidney, Brain nerve, Ischemia, Oxidative injury

Abstract

Background: The acute kidney injury (AKI) may do damage to remote organs. Objective of the study is to investigate effect of seaweed extract (SE) on brain oxidative damage in kidney ischemia/reperfusion rats. Material and Methods: Animals were randomly divided into five groups. SE pre-fed to rats. Results: Kidney I/R may cause oxidative injury in kidneys and brains tissue in rats. SE pre-treatment can decrease lipid peroxidation levels and increase antioxidant enzymes activities in kidney and brain hippocampus of kidney I/R rats. Conclusion: Our results indicate that SE is useful for brain nerve function keeping in kidney I/R rats.

Author Biography

Fang Yu

Drug Research & Production Unit, Faculty of Pharmacy, Obafemi Awolowo University, Ile-Ife, Nigeria

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Published

2016-08-12

How to Cite

Yu, F., Liang, H., & Xin, S. (2016). RENAL ISCHEMIA REPERFUSION CAUSES BRAIN HIPPOCAMPUS OXIDATIVE DAMAGE AND INHIBITION EFFECT. African Journal of Traditional, Complementary and Alternative Medicines, 13(5), 61–66. https://doi.org/10.21010/ajtcam.v13i5.9

Issue

Vol. 13 No. 5 (2016)

Section

Research Papers

License

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