A PILOT STUDY ON THE EFFECT OF CATHA EDULIS FROSK., (CELASTRACEAE) ON METABOLIC SYNDROME IN WOKW RATS

Authors

  • Samira Abdulla Mahmood
  • U. Lindequist

Keywords:

Catha edulis, WOKW rats, metabolic syndrome

Abstract

This study investigated the effect of Catha edulis (khat) on some important parameters of the metabolic syndrome in Wistar Ottawa Karlsburg W (WOKW ) rat. The animals were fed with the standard chow containing 5% air dried pulverized khat leaves for 14 days; followed by the standard chow for16 days. The khat leaves were sorted into green (khat light; KL) and crimson (khat dark; KD) leaves. The control rats were fed on standard chow. Blood glucose (G), serum insulin, serum leptin and serum lipids (triglycerides, total cholesterol, HDL-, LDL-, and VLDL cholesterol) were determined. Feeding with khat leaves reduced the body weight and the triglyceride level of the animals. The effect of KD on these parameters was stronger than that of KL. KD lowered the blood glucose concentration and the leptin content whereas KL was inactive. The khat intake had no significant influence on serum insulin, total serum cholesterol, HDL-, LDL- and VLDL-cholesterol.

Author Biographies

Samira Abdulla Mahmood

Department of Pharmacology, Faculty of Medicine and Health Sciences, Aden University, Aden, Yemen

U. Lindequist

Institute of Pharmacy, Department of Pharmaceutical Biology, Ernst-Moritz-Arndt-University Greifswald, Germany

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Published

2008-04-08

How to Cite

Mahmood, S. A., & Lindequist, U. (2008). A PILOT STUDY ON THE EFFECT OF CATHA EDULIS FROSK., (CELASTRACEAE) ON METABOLIC SYNDROME IN WOKW RATS. African Journal of Traditional, Complementary and Alternative Medicines, 5(3), 271–277. Retrieved from https://journals.athmsi.org/index.php/ajtcam/article/view/421

Issue

Vol. 5 No. 3 (2008)

Section

Research Papers

License

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