THE BIOLOGICAL ACTIVITIES OF HYPERICUM PERFORATUM L.

Authors

  • Gulten Okmen
  • Neslihan Balpınar

DOI:

https://doi.org/10.21010/ajtcam.v14i1.23

Keywords:

Hypericum, Mastitis, Antibacterial activity, Antioxidant activity, Antimutagenic activity

Abstract

Background: Mastitis reduces milk yield and alters milk composition. Antibiotics are widely used in the treatment of the disease. However, this widespread use of antibiotics causes both antibiotic residues in milks and antibiotic resistance developed in bacteria. Today’s researches are focused on discovering and using new antibiotics against bacteria. Objective: The aim of this work was to investigate the antibacterial effects of Hypericum perforatum L. extracts against mastitis pathogens, and its other biological activities. Material and Methods: The extracts were tested by disc diffusion assay. The MIC was evaluated on plant extracts as antibacterial activity. The non-enzymatic antioxidant activity was determined using DPPH as a free radical. Results: The extract showed maximum inhibition zone against two bacteria (Coagulase-negative staphylococci- 33 and 37; CNS 33 and 37), and the zone was 17 mm. A bacterium (CNS – 22) showed the lowest sensitivity to 812,5 µg /mL concentration. In addition, the extract was tested against the stable DPPH (2,2-diphenyl-1-picryl-hydrazyl-hydrate) free-radical for antioxidant activity. As a result, the extract displayed a strong antioxidant activity (trolox equivalent: 0,83 mM). Conclusion: The extract of Hypericum perforatum have antibacterial, antioxidant and antimutagenic potentials.

Author Biography

Gulten Okmen

Department of Biology Assoc. Prof. Dr.

Downloads

Published

2016-11-23

How to Cite

Okmen, G., & Balpınar, N. (2016). THE BIOLOGICAL ACTIVITIES OF HYPERICUM PERFORATUM L. African Journal of Traditional, Complementary and Alternative Medicines, 14(1), 213–218. https://doi.org/10.21010/ajtcam.v14i1.23

Issue

Vol. 14 No. 1 (2017)

Section

Research Papers

License

Copyright: Creative Commons Attribution CC.

This license lets others distribute, remix, tweak, and build upon your work, even commercially, as long as they credit you for the original creation. This is the most accommodating of licenses offered. Recommended for maximum dissemination and use of licensed materials. View License Deed | View Legal Code Authors can also self-archive their manuscripts immediately and enable public access from their institution's repository. This is the version that has been accepted for publication and which typically includes author-incorporated changes suggested during submission, peer review and in editor-author communications.