ANTIBIOTIC SUSCEPTIBILITY PATTERN OF ESCHRICHIA COLI ISOLATES FROM CLINICAL SPECIMENS AT PIMS, ISLAMABAD

Authors

  • Jafar Khan Department of Chemistry Government College Ara Khel FR Kohat KPK Pakistan
  • Irum Khalil
  • Naser M. AbdEl-Salam
  • Sehrish Liaqat
  • Naila Younas
  • Sameerah Mushtaq
  • Riaz Ullah

DOI:

https://doi.org/10.21010/ajtcam.v12i6.4S

Keywords:

Susceptibility pattern, Eschrichia coli, PIMS

Abstract

Background: E. coli is the most common producer of extended spectrum beta lactamase enzyme (ESBL) which confers broad spectrum resistance to antibiotics like penicillin, cephalosporin and monobactum. Methods and Materials: The present study was carried out at Pakistan Institute of Medical Sciences, Islamabad. The marked resistance was viewed against amoxicilline-clavulanic acid, ceftriaxone and ceftazidime. The most effective drugs established were sulbactum-cefoparazone, amikacin, pepircillin-tazobactum. A total of 220 samples of wide range were selected, i.e., blood, urine, pus, sputum, etc. and were analyzed using various techniques of Gram staining and biochemical identification. Results: After performing antibiotic sensitivity tests, 83% samples came out to be ESBL positive and 17% were ESBL negative. Conclusion: It was concluded that to ensure adequate treatment of infections arising especially from urinary pathogens and controlling spread of bacterial resistant strains, the continuous monitoring by bacterial susceptibility testing is essential.

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Published

2015-11-03

How to Cite

Khan, J., Khalil, I., AbdEl-Salam, N. M., Liaqat, S., Younas, N., Mushtaq, S., & Ullah, R. (2015). ANTIBIOTIC SUSCEPTIBILITY PATTERN OF ESCHRICHIA COLI ISOLATES FROM CLINICAL SPECIMENS AT PIMS, ISLAMABAD. African Journal of Traditional, Complementary and Alternative Medicines, 12(Suppl), 62–69. https://doi.org/10.21010/ajtcam.v12i6.4S

Issue

Vol. 12 (2015): Special Issue

Section

Research Papers

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