AN ALTERNATIVE HEPATOPROTECTIVE AND ANTIOXIDANT AGENT: THE GERANIUM

Authors

  • Mirandeli Bautista-Avila Universidad Autónoma del Estado de Hidalgo, Abasolo N. 600, Colonia Centro, C.P. 42000. Pachuca, Hidalgo; México
  • Eduardo Madrigal-Santillán Laboratorio de Medicina de Conservación Escuela Superior de Medicina, IPN, México
  • Angel Morales-González Escuela Superior de Computo, IPN, México
  • Juan A. Gayosso-de-Lucio Universidad Autónoma del Estado de Hidalgo, Abasolo N. 600, Colonia Centro, C.P. 42000. Pachuca, Hidalgo; México
  • Eduardo Madrigal-Bujaidar Departamento de Farmacia, ENCB, IPN, México
  • German Chamorro-Cevallo Departamento de Farmacia, ENCB, IPN, México
  • Isela Alvarez-González Departamento de Farmacia, ENCB, IPN, México
  • Juana Benedi Universidad Autónoma de Madrid, Facultad de Farmacia, Ciudad Universitaria, Plaza de Ramón y Cajal S/N, 28040 Madrid
  • José Leopoldo Aguilar-Faisal Laboratorio de Medicina de Conservación Escuela Superior de Medicina, IPN, México
  • Jose A. Morales-González Laboratorio de Medicina de Conservación Escuela Superior de Medicina, IPN, México

DOI:

https://doi.org/10.21010/ajtcam.v12i4.15

Keywords:

Geranium, Polyphenolic compounds, Tannins, Ethanol.

Abstract

The Geranium genus is taxonomically classified within the family Geraniaceae Juss, which includes 5-11 genera and nearly 750 species in total. The best-known genera of this family are Geranium, consisting largely of wild plants, and Pelargonium, consisting largely of ornamental plants. Traditional uses include as an antiseptic in wounds and as an antipyretic by infusion of the plant. Currently, eight different species of geraniums belonging to the family Geraniaceae have been identified in Hidalgo State in Central Mexico, and no chemical or pharmacological studies have been carried out in any of these eight species. All phytochemical studies on these species indicate the presence of polyphenolic compounds, including tannins, which are characterized as water-soluble compounds with molecular weights between 500 and 30,000 g/mol. These and other compounds warrant the exploration of the Germanium genus for uses related to ethanol-induced hepatotoxicity.

Author Biography

Mirandeli Bautista-Avila, Universidad Autónoma del Estado de Hidalgo, Abasolo N. 600, Colonia Centro, C.P. 42000. Pachuca, Hidalgo; México

Área Académica de Farmacia, ICSa, UAEH

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Published

2015-06-27

How to Cite

Bautista-Avila, M., Madrigal-Santillán, E., Morales-González, A., Gayosso-de-Lucio, J. A., Madrigal-Bujaidar, E., Chamorro-Cevallo, G., Alvarez-González, I., Benedi, J., Aguilar-Faisal, J. L., & Morales-González, J. A. (2015). AN ALTERNATIVE HEPATOPROTECTIVE AND ANTIOXIDANT AGENT: THE GERANIUM. African Journal of Traditional, Complementary and Alternative Medicines, 12(4), 96–105. https://doi.org/10.21010/ajtcam.v12i4.15

Issue

Section

Review

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