STUDY ON ANTI-ATHEROSCLEROTIC EFFECT OF SUXIAO JIUXIN PILL AND ITS MECHANISM

Authors

  • Qing-Xu Guo
  • Jun Zhang
  • Yu-Qing Li
  • Gui-Fu Zhang

Keywords:

Suxiao Jiuxin Pill, atherosclerosis, atorvastatin

Abstract

Background: Suxiao Jiuxin Pill is composed of Ligusticum wallichii, Borneolum Syntheticum and other drugs; it has qi promoting and blood circulation activating, meridian dredging and pain relieving efficacies. The objective of this paper is to study the effect of Suxiao Jiuxin Pill (quick-acting heart reliever), in atherosclerosis (AS) rat model and explore the mechanism for its prevention and treatment of AS. Materials and Methods: AS rat model was established by high cholesterol diet and single intra-peritoneal injection of increased dose of vitamin D3. Results: Compared with the model group, Suxiao Jiuxin Pill medium- and high-dose groups and atorvastatin group can effectively regulate lipid metabolism. Conclusion: We conclude that Suxiao Jiuxin Pill has a good hypo-lipidemic effect, and can inhibit the occurrence and development of AS.

Author Biography

Qing-Xu Guo

The Military General Hospital of BeiJing PLASurgical Dept Vascular Diseases,Beijing,China

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Published

2013-10-28

How to Cite

Guo, Q.-X., Zhang, J., Li, Y.-Q., & Zhang, G.-F. (2013). STUDY ON ANTI-ATHEROSCLEROTIC EFFECT OF SUXIAO JIUXIN PILL AND ITS MECHANISM. African Journal of Traditional, Complementary and Alternative Medicines, 11(1), 97–102. Retrieved from https://journals.athmsi.org/index.php/ajtcam/article/view/2191

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Section

Research Papers