A STUDY ON THE INHIBITORY EFFECT OF SOLANUM LYRATUM THUNB EXTRACT ON LEWIS LUNG CARCINOMA LINES

Authors

  • Zhi-Ming Xiao
  • Ai-Min Wang
  • Xiao-Yan Wang
  • Shou-Rong Shen

Keywords:

Solanum lyratum Thunb, tumour-bearing mice, anti-tumour effect

Abstract

The objective of this paper was to observe the effects of Solanum lyratum Thunb extract on tumour inhibition, immune function and survival time of tumour-bearing mice. Lung carcinoma-bearing mouse model was established, the tumour-bearing mice were divided into model group, CTX group, Solanum lyratum Thunb extract high-dose group and low-dose group. By the examination of tumour inhibition rate of Solanum lyratum Thunb extract in Lewis lung carcinoma-bearing mice and determination of the number of NK cells and T cell subsets, the survival rate of tumour-bearing mice was observed. Solanum lyratum Thunb extract had some anti-tumour effect in Lewis tumour-bearing mice. The tumour inhibition rate of high-dose group reached 46.28%, and the tumour inhibition rate of low-dose group was 31.42%. Solanum lyratum Thunb extract can improve the NK cell activity of Lewis tumour-bearing mice, increase the number of CD4 cells in the tumour-bearing mice, and significantly increase the survival rate of tumour-bearing mice. The study concluded that Solanum lyratum Thunb extract has some anti-tumour effect and can improve immune function and survival rate of tumour-bearing mice.

Author Biography

Zhi-Ming Xiao

Department of Gastroenterology, the Third Hospital of Xiangya, Central South University, Changsha 410013, Hunan Province, China

Downloads

Published

2013-09-20

How to Cite

Xiao, Z.-M., Wang, A.-M., Wang, X.-Y., & Shen, S.-R. (2013). A STUDY ON THE INHIBITORY EFFECT OF SOLANUM LYRATUM THUNB EXTRACT ON LEWIS LUNG CARCINOMA LINES. African Journal of Traditional, Complementary and Alternative Medicines, 10(6), 444–448. Retrieved from https://journals.athmsi.org/index.php/ajtcam/article/view/2096

Issue

Section

Research Papers