A STUDY ON THE INHIBITORY EFFECT OF MATRINE ON GASTRIC CANCER SGC-7901 CELLS

Authors

  • Shimao Song
  • Shengming Zhu
  • Zhiguo Zhang
  • Zhengying Mo
  • Qing Ke
  • Zhiguo Luo

Keywords:

Matrine, SGC-7901, MTT assay

Abstract

The objective of this paper was to investigate the antitumour mechanism of action of matrine by studying its inhibitory effect on gastric cancer SGC-7901 cells. SGC-7901 cells were chosen, and cell-killing capacity of matrine on gastric cancer SGC-7901 cells was determined using MTT assay and single PI staining assay. The results showed that matrine had an inhibitory effect on gastric cancer SGC-7901 cells, which was somewhat dose-dependent. The study concluded that matrine has a significant in-vitro inhibitory effect on SGC-7901 tumour cells, influences cell cycle of SGC-7901 cells, and induces their apoptosis.

Author Biography

Shimao Song

Department of Oncology, Taihe Hospital Affiliated of Hubei University of Medicine, Shiyan 442000,China.

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Published

2013-09-20

How to Cite

Song, S., Zhu, S., Zhang, Z., Mo, Z., Ke, Q., & Luo, Z. (2013). A STUDY ON THE INHIBITORY EFFECT OF MATRINE ON GASTRIC CANCER SGC-7901 CELLS. African Journal of Traditional, Complementary and Alternative Medicines, 10(6), 435–438. Retrieved from https://journals.athmsi.org/index.php/ajtcam/article/view/2094

Issue

Vol. 10 No. 6 (2013)

Section

Research Papers

License

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