THE EFFECTS OF β-ELEMENE ON THE EXPRESSION OF MTOR, HIF-1Α, SURVIVIN IN LUNG ADENOCARCINOMA A549 CELL
Abstract
The purpose of this manuscript was to study the regulation effects of β-elemene combined with radiotherapy on three different gene expressions in lung adenocarcinoma A549 cell. mTOR gene, HIF-1α gene, Survivin gene were included in the gene group. Cell culture and RT-PCR were applied to finish this research. Hypoxia Control group, Hypoxia β-elemene group, Hypoxia β-elemene combined with irradiation group were set to compare the differences of three different gene expressions. The most active effects were found in the group of Hypoxia irradiation combined with β-elemene. In this group, the mTOR gene, HIF-1α gene, Survivin gene expressions were all down-regulated when compared with the single treatment groups, and there were significantly statistical differences.Downloads
Published
2013-04-19
How to Cite
Tong, E., Xu, Y., Li, G., Zou, K., & Zou, L. (2013). THE EFFECTS OF β-ELEMENE ON THE EXPRESSION OF MTOR, HIF-1Α, SURVIVIN IN LUNG ADENOCARCINOMA A549 CELL. African Journal of Traditional, Complementary and Alternative Medicines, 10(4), 18–23. Retrieved from https://journals.athmsi.org/index.php/ajtcam/article/view/1831
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Research Papers
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