SPECIFIC NEUROPROTECTIVE EFFECTS OF MANUAL STIMULATION OF REAL ACUPOINTS VERSUS NON-ACUPOINTS IN RATS AFTER MIDDLE CEREBRAL ARTERY OCCLUSION

Authors

  • Ling Xin Li Postgraduate Department of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.
  • Xiao Nong Fan Department of Acupuncture and Moxibustion, First Hospital Affiliated to Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.
  • Zhi Hong Meng Department of Acupuncture and Moxibustion, First Hospital Affiliated to Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.
  • Xue Min Shi Department of Acupuncture and Moxibustion, First Hospital Affiliated to Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.
  • Ding Luo Postgraduate Department of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.
  • Ya Nan Zhang Postgraduate Department of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.

Keywords:

specificity, real acupoint, non-acupoint, middle cerebral artery occlusion, animal experimentation

Abstract

The objective of this study was to investigate the effectiveness and specific effects of acupuncture on ischemic-induced damage in rats after permanent middle cerebral artery occlusion. Cerebral ischemia was induced by middle cerebral artery occlusion in male Wistar rats. The rats were divided into the following 4 groups: normal controls, ischemic, real acupuncture-treated (Shuigou, DU26), and non-acupoint-treated groups. On the third postoperative day, neurological deficit scores, cerebral blood flow, infarction volume, and neuronal cell death counts were measured. In the real acupuncture-treated group, the neurological deficit scores and cerebral blood flow were improved (p < 0.05) and the infarction volume and neuronal cell death counts were reduced (p < 0.01) compared to the ischemic and non-acupoint-treated groups. The present study demonstrated that real acupuncture was effective against focal ischemia-induced damage in rats after middle cerebral artery occlusion, and the effects were specifically related to the right needling location.

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Published

2013-04-20

How to Cite

Li, L. X., Fan, X. N., Meng, Z. H., Shi, X. M., Luo, D., & Zhang, Y. N. (2013). SPECIFIC NEUROPROTECTIVE EFFECTS OF MANUAL STIMULATION OF REAL ACUPOINTS VERSUS NON-ACUPOINTS IN RATS AFTER MIDDLE CEREBRAL ARTERY OCCLUSION. African Journal of Traditional, Complementary and Alternative Medicines, 10(4), 186–195. Retrieved from https://journals.athmsi.org/index.php/ajtcam/article/view/1692

Issue

Vol. 10 No. 4 (2013)

Section

Research Papers

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