EFFECTS OF METHANOLIC EXTRACT OF MORINGA OLEIFERA LEAVES ON SEMEN AND BIOCHEMICAL PARAMETERS IN CRYPTORCHID RATS

Authors

  • Ayobami Oladele Afolabi Department of Physiology, College of Health Sciences, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria
  • Hameed Adeola Aderoju Department of Physiology, College of Health Sciences, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria
  • Isiaka Abdullateef Alagbonsi Kogi state university, Anyigba

Keywords:

Moringa oleifera, Cryptorchidism, anti-oxidant, semen parameters

Abstract

While anti-oxidant effects of Moringa oleifera in much oxidative stress related diseases have been well reported, cryptorchidism on the other hand has been shown to cause oxidative stress. However, study is scanty on the likely role of Moringa oleifera in reducing cryptorchidism-induced oxidative stress in rats has not been studied. The present study looked into the effects of methanolic extract of Moringa oleifera leaves (MEMO) on semen and biochemical parameters in cryptorchid rats. Twenty male albino rats (200-250g) were randomly divided into 4 groups (n=5 each). Groups A and B were sham-operated and treated with corn-oil and 200mg/kg of MEMO respectively, while groups C and D were rendered cryptorchid and also treated with corn-oil and 200mg/kg of MEMO respectively. Cryptorchid rats had lower testicular weight, sperm count, germ cell count, testicular superoxide dismutase (SOD) concentration, testicular total protein and higher testicular malondialdehyde (MDA) concentration compared to sham-operated rats. MEMO had no significant effect on testicular weight and MDA concentration, while it significantly increased sperm count, germ cell count, testicular SOD and total protein in the cryptorchid rats. The present study suggests that MEMO ameliorates cryptorchidism associated germ cell loss and oxidative stress.

Author Biography

Isiaka Abdullateef Alagbonsi, Kogi state university, Anyigba

Physiology, Assistant lecturer

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Published

2013-06-23

How to Cite

Afolabi, A. O., Aderoju, H. A., & Alagbonsi, I. A. (2013). EFFECTS OF METHANOLIC EXTRACT OF MORINGA OLEIFERA LEAVES ON SEMEN AND BIOCHEMICAL PARAMETERS IN CRYPTORCHID RATS. African Journal of Traditional, Complementary and Alternative Medicines, 10(5), 230–235. Retrieved from https://journals.athmsi.org/index.php/ajtcam/article/view/1632

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Section

Research Papers