IN VITRO ANTIPLASMODIAL PROPERTIES OF FLACOURTIA FLAVESCENS WILLD.   (FLACOURTIACEAE) AND RYTIGYNIA CANTHIOIDES (BENTH.) ROBYNS (RUBIACEAE)

M. A. Djikpo-Tchibozo1; S. D. Karou; S. Sanon; F. Toukourou; C. de Souza

IN VITRO ANTIPLASMODIAL PROPERTIES OF FLACOURTIA FLAVESCENS WILLD. (FLACOURTIACEAE) AND RYTIGYNIA CANTHIOIDES (BENTH.) ROBYNS (RUBIACEAE)

Authors

M. A. Djikpo-Tchibozo1
S. D. Karou
S. Sanon
F. Toukourou
C. de Souza

Keywords:

Flacourtia flavescens, Rytigynia canthioides, Plasmodium falciparum, antiplasmodial

Abstract

The present study was conducted to investigate the in vitro antimalarial activity of Flacourtia flavescens Willd. (Flacourtiaceae) and Rytigynia canthioides (Benth.) Robyns (Rubiaceae). These two plants are used in Benin folk medicine to treat malaria and fever. Antimalarial activity was assayed on fresh clinical isolates of chloroquine resistant Plasmodium falciparum using the in vitro semi-microtest. The results revealed that the IC50 varied from 1.55 to 22.36Âµg/ml. F. flavescens hydro methanol extract was more active than R. canthioides. The study demonstrated scientific rationale behind the traditional usage of these plants, however further bioactivity guided phytochemical analyses are necessary to identify the active principles.

Author Biography

S. D. Karou

Centre de Recherche et de Formation sur les Plantes Médicinales (CERFOPLAM), Université de Lomé, Togo

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Published

2010-09-14

How to Cite

Djikpo-Tchibozo1, M. A., Karou, S. D., Sanon, S., Toukourou, F., & de Souza, C. (2010). IN VITRO ANTIPLASMODIAL PROPERTIES OF FLACOURTIA FLAVESCENS WILLD. (FLACOURTIACEAE) AND RYTIGYNIA CANTHIOIDES (BENTH.) ROBYNS (RUBIACEAE). African Journal of Traditional, Complementary and Alternative Medicines, 8(1), 66–68. Retrieved from https://journals.athmsi.org/index.php/ajtcam/article/view/1174

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Issue

Vol. 8 No. 1 (2011)

Section

Research Papers

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