STUDY ON ANTIGENOTOXIC EFFECTS OF MOROCCAN MEDICINAL PLANTS AND SPICES USING THE WHITE/WHITEP+ SOMATIC ASSAY IN DROSOPHILA

Authors

  • N. Mezzoug
  • J. Abrini
  • A. M. Serano
  • A. Alonso-Moraga
  • M. Idaomar

Keywords:

Antigenotoxicity, Medicinal plants, Spices, w/wP P SMART assay, Drosophila, MMS.

Abstract

The antigenotoxic action of a selection of medicinal plants and spices from Morocco including laurel (Laurus nobilis), rosemary (Rosmarinus officinalis), verbena (Verbena triphylla), fenugreek (Trigonella foenum-graecum) and nutmeg (Myristica fragrens) was assessed using the eye white/whiteP+P (w/wP+P) Somatic Mutation and Recombination Test (SMART) assay of Drosophila melanogaster. Methyl methanesulfonate (MMS) was used as a positive mutagenic compound inducing high frequencies of spots in Drosophila larvae. The frequencies of spots per eyes of a treated series are compared to those of its concurrent positive control series using P2P- test for evaluation of the antigenotoxic effect. The nutmeg at 1% (w/v) demonstrated a marked decrease in MMS-induced spots with an inhibition rate of 50%. Rosemary, fenugreek seeds and laurel showed different inhibition rates with different level of significance.

Author Biographies

N. Mezzoug

Université Abdelmalek Essaâdi, Unité de Biologie Cellulaire et Moléculaire (BCM) BP 2121, 93002 Tétouan, Morocco

J. Abrini

Université Abdelmalek Essaâdi, Unité de Biologie Cellulaire et Moléculaire (BCM) BP 2121, 93002 Tétouan, Morocco

A. M. Serano

Universidad de Córdoba, Departamento de Genética, San Alberto Magno s/n, 14071 Córdoba, Spain.

A. Alonso-Moraga

Universidad de Córdoba, Departamento de Genética, San Alberto Magno s/n, 14071 Córdoba, Spain.

M. Idaomar

Universidad de Córdoba, Departamento de Genética, San Alberto Magno s/n, 14071 Córdoba, Spain.

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Published

2006-05-18

How to Cite

Mezzoug, N., Abrini, J., Serano, A. M., Alonso-Moraga, A., & Idaomar, M. (2006). STUDY ON ANTIGENOTOXIC EFFECTS OF MOROCCAN MEDICINAL PLANTS AND SPICES USING THE WHITE/WHITEP+ SOMATIC ASSAY IN DROSOPHILA. African Journal of Traditional, Complementary and Alternative Medicines, 3(3), 22–31. Retrieved from https://journals.athmsi.org/index.php/ajtcam/article/view/113

Issue

Vol. 3 No. 3 (2006)

Section

Research Papers

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