BLOOD GLUCOSE LOWERING EFFECT OF AQUEOUS LEAF EXTRACTS OF AGERATUM CONYZOIDES IN RATS.

Authors

  • N. Nyunaï
  • N. Njikam
  • C. Mounier
  • P. Pastoureau

Keywords:

Ageratum conyzoides, glucose lowering effect, streptozotocin-diabetic rats

Abstract

This study was undertaken to investigate the effect of aqueous extracts from leaves of Ageratum conyzoides (300mg/kg) on blood glucose in normoglycemic and streptozotocin-diabetic rats. The extract was administered orally and the blood glucose level was measured hourly for 4h. The hypoglycaemic activity was evaluated by comparing with the initial blood glucose level. In streptozotocin-diabetic rats, the aqueous extract from leaves of Ageratum conyzoides showed a significant reduction of blood glucose level of 9.5% after 1hour and 21.3% after 4 hour.

Author Biographies

N. Nyunaï

Laboratoire d’Endocrinologie et de Radioéléments, Institut de Recherches Médicales et d’Etudes des Plantes Médicinales, B.P. 3805 Yaoundé, Cameroun

N. Njikam

bLaboratoire de Physiologie animale, Faculté des Sciences, Université de Yaoundé 1, B.P. 812 Yaoundé. Cameroun

C. Mounier

Laboratoire de lipogenèse hépatique, Université du Québec à Montréal, 1200 St Alexandre, Montréal, Québec, Canada H3B 3H5

P. Pastoureau

Institut de Recherches Servier, 11 rue des Moulineaux, 92150 Suresnes, France

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Published

2006-03-27

How to Cite

Nyunaï, N., Njikam, N., Mounier, C., & Pastoureau, P. (2006). BLOOD GLUCOSE LOWERING EFFECT OF AQUEOUS LEAF EXTRACTS OF AGERATUM CONYZOIDES IN RATS. African Journal of Traditional, Complementary and Alternative Medicines, 3(3), 76–79. Retrieved from https://journals.athmsi.org/index.php/ajtcam/article/view/107

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Section

Research Papers