TY - JOUR AU - Kadjo, Herve A. AU - Adjogoua, Edgard AU - Dia, Ndongo AU - Adagba, Marius AU - Abdoulaye, Ouattara AU - Daniel, Saraka AU - Kouakou, Bertin AU - Ngolo, David C. AU - Coulibaly, Daouda AU - Ndahwouh, Talla Nzussouo AU - Dosso, Mireille PY - 2018/06/18 Y2 - 2024/03/29 TI - DETECTION OF NON-INFLUENZA VIRUSES IN ACUTE RESPIRATORY INFECTIONS IN CHILDREN UNDER FIVE-YEAR-OLD IN COTE D’IVOIRE (JANUARY – DECEMBER 2013) JF - African Journal of Infectious Diseases (AJID) JA - Afr. J. Infect. Dis. VL - 12 IS - 2 SE - Articles DO - 10.21010/Ajid.v12i2.13 UR - https://journals.athmsi.org/index.php/AJID/article/view/5119 SP - 78-88 AB - Background: Influenza sentinel surveillance in Cote d’Ivoire showed that 70% of Acute Respiratory Infections (ARI)cases remained without etiology. This work aims to describe the epidemiological, clinical, and virological pattern ofARI that tested negative for influenza virus, in children under five years old.Materials and Methods: one thousand and fifty nine samples of patients presenting influenza Like Illness (ILI) orSevere Acute Respiratory Infections (SARI) symptoms were tested for other respiratory viruses using multiplex RTPCRassays targeting 10 respiratory viruses.Results: The following pathogens were detected as follows, hRV 31,92% (98/307), hRSV 24.4% (75/329), PIV 20.5%(63/307), HCoV 229E 12,05% (37/307), hMPV 6.2% (19/307), HCoVOC43 1.0% (3/307) and EnV 1.0% (3/307).Among the 1,059 specimens analyzed, 917 (86.6%) were ILI samples and 142 (23.4%) were SARI samples. Theproportion of children infected with at least one virus was 29.8% (273/917) in ILI cases and 23.9% (34/142) in SARIcases. The most prevalent viruses, responsible for ILI cases were hRV with 35.89% (98/273) and hRSV in SARI caseswith 41.2% (14/34) of cases. Among the 1,059 patients, only 22 (2.1%) children presented risk factors related to theseverity of influenza virus infection.Conclusion: This study showed that respiratory viruses play an important role in the etiology of ARI in children. For abetter understanding of the epidemiology of ARI and improved case management, it would be interesting in thiscontext to expand the surveillance of influenza to other respiratory viruses. ER -