ANTIMICROBIAL AND ANTIRADICAL PROPERTIES OF HAMMADA SCOPARIA (POMEL) ILJIN

Authors

  • Aziz Drioiche Moulay Ismaïl University, Faculty of Sciences, Meknes, B.P. 11201 Zitoune Meknes, Morocco
  • Nadia Benhlima Research team on the chemistry of bioactive molecules and environment Moulay Ismaïl University, Faculty of Sciences, Meknes, B.P. 11201 Zitoune Meknes, Morocco
  • Samira Kharchouf Moulay Ismaïl University, Faculty of Sciences, Meknes, B.P. 11201 Zitoune Meknes, Morocco
  • Fadoua EL MAKHOUKHI Moulay Ismaïl University, Faculty of Sciences, Meknes, B.P. 11201 Zitoune Meknes, Morocco
  • Smahane MEHANNED Moulay Ismaïl University, Faculty of Sciences, Meknes, B.P. 11201 Zitoune Meknes, Morocco
  • Imad ADADI Moulay Ismaïl University, Faculty of Sciences, Meknes, B.P. 11201 Zitoune Meknes, Morocco
  • Hicham AAZIZ Moulay Ismaïl University, Faculty of Sciences, Meknes, B.P. 11201 Zitoune Meknes, Morocco
  • Ferdinand Kouoh Elombo Laboratory of Pharmacology, Pharmacokinetics, and Clinical Pharmacy, Faculty of Pharmaceutical and Biological Sciences, Lille, France
  • Bernard Gressier Laboratory of Pharmacology, Pharmacokinetics, and Clinical Pharmacy, Faculty of Pharmaceutical and Biological Sciences, Lille, France
  • Bruno ETO 65, Avenue de l’Hippodrome 62000 Arras, France. E-mail: etobr@laboratoires-tbc.com
  • Touriya Zair Moulay Ismaïl University, Faculty of Sciences, Meknes, B.P. 11201 Zitoune Meknes, Morocco

DOI:

https://doi.org/10.21010/Ajtcam.v16n2.1

Keywords:

polyphenolics, Hammada scoparia, antimicrobial, antifungal, antioxidant

Abstract

Background: Hammada scoparia (Pomel) Iljin (HS), is commonly used by traditional healers in Morocco against microbial and fungal infections. We studied antimicrobial, antifungal and antiradical effects of organic extracts in vitro in order to confirm traditional utilization after phytochemical screening.

Materials and methods: Aerial parts of HS have been extracted by hydro-distillation using Clevenger-type apparatus, and the chemical composition was realized by Gas Chromatography coupled with Mass Spectroscopy (GC/MS). The antioxidant activity has been evaluated using DPPH test, while the antimicrobial tests of HS extract were conducted on twenty-eight bacterial strains and antifungal on twelve fungal strains.

Results: Chemical characterization of HS essential oils (EO) confirmed the presence of carvacrol (82,28%), p-cymene (2,52%), γ-terpinene (2,18%) and Z-caryophyllene (2,04%). Antimicrobial tests of HS extract showed a moderate antibacterial activity without antifungal effect. In addition, HS exhibited a very powerful antiradical activity with IC50 = 1,2 mg/ml compared to that of ascorbic acid (IC50 = 0,5 mg/mL) and butylated hydroxyanisole (0,8 mg/mL).

Conclusion: To our knowledge, this is the first demonstration that HS directly inhibits the growth of microorganisms in vitro, and further validates its traditional use as an antiseptic by traditional Moroccan healers.

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Published

2020-01-09

How to Cite

Drioiche, A., Benhlima, N., Kharchouf, S., EL MAKHOUKHI, F., MEHANNED, S., ADADI, I., AAZIZ, H., Kouoh Elombo, F., Gressier, B., ETO, B., & Zair, T. (2020). ANTIMICROBIAL AND ANTIRADICAL PROPERTIES OF HAMMADA SCOPARIA (POMEL) ILJIN. African Journal of Traditional, Complementary and Alternative Medicines, 16(2), 1–14. https://doi.org/10.21010/Ajtcam.v16n2.1

Issue

Vol. 16 No. 2 (2019)

Section

Research Papers

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